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Prohibited substance

Phentermine hydrochloride [USAN]

CAS 1197-21-3
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Phentermine hydrochloride is a prescription amphetamine-derived stimulant prohibited in cosmetics under EU Annex II. It carries cardiovascular and dependence risks with no skincare role.

Skin benefits

  • No cosmetic benefit
  • Prescription amphetamine-class appetite suppressant
  • Listed for regulatory transparency

Known concerns

  • Sympathomimetic stimulant with cardiovascular risks
  • Banned in cosmetics under EU Annex II prohibited substances
  • Controlled substance in most jurisdictions
  • Potential for abuse and dependence

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.