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Prohibited substance

hydromorphone

CAS 466-99-9
3

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Hydromorphone is a strong prescription opioid painkiller. It is a controlled medicine, never an acceptable cosmetic ingredient, and any presence in a cosmetic product would breach EU and international regulations.

Skin benefits

  • No legitimate cosmetic benefit identified
  • Medical use as a strong analgesic under strict prescription control

Known concerns

  • Schedule II opioid analgesic, not a cosmetic ingredient
  • Risk of respiratory depression and addiction if absorbed
  • Listed in EU Cosmetics Regulation Annex II (prohibited)
  • Controlled substance under international drug treaties

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related prohibited substances

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.