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Prohibited substance

Atropine, its salts and derivatives

CAS 51-55-8
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Atropine is a tropane-alkaloid medicine listed under EU Cosmetics Regulation Annex II among substances prohibited in cosmetic products. Its anticholinergic effects make any cosmetic use unsafe.

Skin benefits

  • No legitimate cosmetic benefit
  • Important pharmaceutical anticholinergic medicine

Known concerns

  • Anticholinergic alkaloid, a prescription medicine
  • EU Cosmetics Regulation Annex II explicitly bans atropine and its salts and derivatives
  • Causes mydriasis, tachycardia and systemic toxicity
  • Even small percutaneous doses can be hazardous
  • Acutely toxic at low doses

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related prohibited substances

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.