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Prohibited substance

Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- its salts

CAS 130-95-0
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

This entry corresponds to quinine and its salts, a cinchona alkaloid prohibited in cosmetics under EU Annex II. It carries systemic, sensitization and photosensitivity risks and has no place in skincare formulations.

Skin benefits

  • No cosmetic benefit
  • Quinine alkaloid is a pharmaceutical only
  • Listed for regulatory transparency

Known concerns

  • Quinine and salts are EU Annex II prohibited cosmetic substances
  • Risk of cinchonism, ototoxicity and serious cardiac effects
  • Documented contact sensitization and photosensitivity
  • Strictly limited to medicinal use under prescription

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related prohibited substances

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.