Prohibited substance
4-Benzyloxyphenol and 4-ethoxyphenol
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Monobenzone and 4-ethoxyphenol are depigmenting compounds banned in EU cosmetics. Monobenzone in particular causes permanent loss of skin pigment and is restricted to medical use only.
Skin benefits
- 4-Benzyloxyphenol (monobenzone) is a prescription depigmenting drug for severe vitiligo
- No legitimate cosmetic benefit
Known concerns
- Listed on EU Annex II of substances prohibited in cosmetic products
- Monobenzone causes permanent, irreversible loss of skin pigment
- Strong contact sensitiser (GHS H317) and eye irritant (H319)
- Can cause depigmentation at distant skin sites, not just where applied
- Use outside medical supervision can cause permanent disfigurement
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related prohibited substances
Check your shelf
Find 4-Benzyloxyphenol and 4-ethoxyphenol in your products.
Scan any cosmetic product with LuxSense to see if it contains 4-Benzyloxyphenol and 4-ethoxyphenol and get a full ingredient breakdown with safety scores.
This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.