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Prohibited substance

phenmetrazine

CAS 134-49-6
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Phenmetrazine is a prescription stimulant drug historically used for appetite suppression. It has no place in cosmetics and is listed among substances banned from personal care products in the EU.

Skin benefits

  • No legitimate cosmetic benefit identified
  • Historically used as a prescription appetite suppressant under medical supervision

Known concerns

  • Scheduled CNS stimulant (amphetamine-class) drug, not a cosmetic ingredient
  • Cardiovascular and psychiatric risks if absorbed
  • Listed in EU Cosmetics Regulation Annex II (prohibited substances)
  • Controlled substance under international drug treaties

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Check your shelf

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.