Skip to content

Other

PEG-220

CAS 25322-68-3
86

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A high molecular weight polyethylene glycol (~220 EO units) acting as a thickener, binder, and film-former in cosmetic products, with negligible skin penetration due to its large polymer size.

PEG-220 is a polyethylene glycol polymer with an average of 220 moles of ethylene oxide per molecule, giving it a molecular weight in the range where skin penetration is essentially negligible. It functions primarily as a viscosity-controlling agent, binder, and humectant in cosmetic formulations. EU Regulation (EC) 1223/2009 does not restrict high molecular weight PEG polymers. Purity considerations (residual ethylene oxide, 1,4-dioxane, and catalyst metals) are the primary quality concerns, and compliance with SCCS Notes of Guidance ensures safety at typical use concentrations.

Skin benefits

  • Thickens and stabilizes cosmetic formulations
  • Provides humectant film on skin surface
  • Inert polymer with broad formulation compatibility

Known concerns

  • Residual 1,4-dioxane and ethylene oxide must be controlled per SCCS standards
  • May contain trace heavy metal catalysts from polymerization

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related others

Check your shelf

Find PEG-220 in your products.

Scan any cosmetic product with LuxSense to see if it contains PEG-220 and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.