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Prohibited hair dye intermediate

Ethanol, 2-[(4-amino-2-methyl-5-nitrophenyl)amino]- and its salts

CAS 82576-75-8
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A nitro-aniline hair dye coupler that has been prohibited from cosmetic use throughout the EU because of clear genotoxicity concerns common to this aromatic amine chemical family of dye precursors.

Skin benefits

  • Historically a hair dye intermediate; now no permitted cosmetic use
  • Provided color in older oxidative dye systems before being phased out

Known concerns

  • Aromatic amine prohibited in EU cosmetics (Annex II) due to genotoxicity concerns
  • SCCS reviews flagged risk of mutagenicity for this aniline-type structure
  • Potential skin sensitizer typical of nitro-aniline hair dyes
  • Possible systemic exposure through scalp absorption

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related prohibited hair dye intermediates

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.