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Prohibited hair dye intermediate

4-FLUORO-6-METHYL-M-PHENYLENEDIAMINE SULFATE

CAS 173994-76-8 / 217311-43-8
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

This fluorinated m-phenylenediamine derivative was a candidate hair dye that the EU has banned. Like related compounds, it carries a high risk of allergic skin reactions and lacks safety clearance.

Skin benefits

  • Was investigated as a permanent hair dye intermediate
  • Of academic interest in fluorinated aromatic chemistry

Known concerns

  • Banned in EU cosmetics (Annex II)
  • m-Phenylenediamine class with strong skin sensitization potential
  • Risk of allergic contact dermatitis and cross reactivity
  • Insufficient safety data and no positive SCCS opinion

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related prohibited hair dye intermediates

5
4-Ethoxy-m-phenylenediamine and its salts
Prohibited hair dye intermediate
 6
4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE
Prohibited hair dye intermediate
 8
Ethanol, 2-[(4-amino-2-methyl-5-nitrophenyl)amino]- and its salts
Prohibited hair dye intermediate

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.