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Prohibited hair dye intermediate

4-Ethoxy-m-phenylenediamine and its salts

CAS 67801-06-3 / 5862-77-1 / 68015-98-5 / 6219-69-8
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

4-ethoxy-m-phenylenediamine is a hair dye chemical that the EU banned because of strong allergic and toxicity concerns. It is part of a class of substances notorious for severe skin reactions.

Skin benefits

  • Was a candidate oxidative hair dye intermediate
  • Of historical interest in dye chemistry

Known concerns

  • Banned in EU cosmetics (Annex II)
  • m-Phenylenediamine derivatives are strong skin sensitizers
  • Risk of severe allergic contact dermatitis
  • Possible mutagenic effects characteristic of the class

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related prohibited hair dye intermediates

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4-FLUORO-6-METHYL-M-PHENYLENEDIAMINE SULFATE
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4,6-BIS(2-HYDROXYETHOXY)-M-PHENYLENEDIAMINE
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 8
Ethanol, 2-[(4-amino-2-methyl-5-nitrophenyl)amino]- and its salts
Prohibited hair dye intermediate

Same plant / compound family

25
4-ETHOXY-M-PHENYLENEDIAMINE
Hair Conditioning
 25
4-ETHOXY-M-PHENYLENEDIAMINE SULFATE
Hair dye intermediate

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.