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Skin Conditioning

DECAPEPTIDE-65

67

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic ten-amino-acid peptide used as a skin-conditioning agent. Designer decapeptide with limited independent safety/efficacy literature.

Decapeptide-65 is a ten-residue synthetic peptide developed for cosmetic skin-conditioning use. Larger designer peptides like decapeptides are dosed at parts-per-million levels in serums and creams; their size makes them poorly absorbed across intact skin, so systemic exposure is minimal. No independent CIR or SCCS review of this specific INCI is available; efficacy claims rely on supplier-sponsored studies. Listed in EU CosIng. Conservative tier: yellow with low evidence.

Function

SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Trace-level skin conditioning
  • Low sensitization potential
  • Compatible with most leave-on formats

Known concerns

  • Limited independent safety data
  • No CIR/SCCS monograph
  • Supplier-driven efficacy claims

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.