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3-(Piperazin-1-yl)-benzo[d]isothiazole hydrochloride

CAS 87691-88-1
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A pharmaceutical intermediate (used in synthesis of the antipsychotic ziprasidone). Not a cosmetic ingredient — has biological activity on serotonin/dopamine receptors. Should not appear in finished personal-care products.

Skin benefits

  • No cosmetic benefit established

Known concerns

  • Pharmaceutical intermediate (ziprasidone synthesis) — not a cosmetic ingredient
  • Drug-class scaffold with CNS pharmacology
  • No CIR/SCCS review; no legitimate cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.