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1,5-Di-(beta-hydroxyethylamino)-2-nitro-4-chlorobenzene (see note 17)

CAS 109023-83-8
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A chloronitrobenzene derivative with multiple GHS hazard statements (H315, H319, H335) for irritation, permitted in hair dye use only up to 0.1% concentration.

This compound is a chloronitrobenzene bearing two hydroxyethylamino substituents, used as an oxidative hair dye intermediate. It carries three GHS hazard classifications for irritation (skin, eye, and respiratory, H315/H319/H335). Under EU cosmetic regulation it is subject to a maximum permitted concentration of 0.1% when used in hair dye formulations, and must be labelled with appropriate hazard warnings. The nitro and chloro substituents both contribute to toxicological concern.

Known concerns

  • Skin irritation hazard (H315)
  • Eye irritation hazard (H319)
  • Respiratory irritation hazard (H335)
  • Maximum permitted concentration 0.1% in hair dyes

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.