ZANTHOXYLUM PIPERITUM PEEL EXTRACT

Antimicrobial

78

Good

CAS Number: 97404-53-0

About ZANTHOXYLUM PIPERITUM PEEL EXTRACT

Sichuan pepper peel extract — a natural antimicrobial and preservative used in cosmetics. CIR-reviewed as safe when formulated to be non-sensitizing.

Detailed Analysis

Zanthoxylum piperitum peel extract contains hydroxy-alpha-sanshool, flavonoids, and essential oil compounds with antimicrobial, anti-inflammatory, and mild numbing properties. CIR Expert Panel concluded it is safe for cosmetic use at described concentrations (up to 0.0022% in skincare) when formulated to be non-sensitizing. A 110-subject HRIPT with 2% concentration showed no irritation or sensitization. CosIng-listed as antimicrobial. The fruit/peel extract can cause numbing sensation and may irritate very sensitive skin. Distinguished from the more irritating CO2 extract.

What It Does

ANTIMICROBIAL

Skin Benefits

  • Natural antimicrobial and preservative
  • Anti-inflammatory properties
  • May help with acne-prone skin
  • Can reduce body odor

Known Concerns

  • Can cause numbing/tingling sensation on skin
  • Fruit extract may irritate very sensitive skin
  • Contains limonene — a fragrance allergen
  • Very low maximum use concentrations in skincare (0.0022%)

Safety Score

78

Good

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.