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Preservative

TRIS(N-HYDROXYETHYL) HEXAHYDROTRIAZINE

CAS 4719-04-4
20

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A hexahydrotriazine biocide that slowly releases formaldehyde to preserve formulas. Formaldehyde is a known sensitizer and IARC Group 1 carcinogen, so this preservative is best avoided in cosmetics.

Function

SKIN CONDITIONINGSKIN PROTECTING

Skin benefits

  • Effective broad-spectrum biocide
  • Used in metalworking and industrial preservation
  • Long shelf life

Known concerns

  • Formaldehyde releaser — sensitization and contact dermatitis
  • Formaldehyde is IARC Group 1 carcinogen by inhalation
  • Not on EU positive list of cosmetic preservatives

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related preservatives

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.