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Preservative

2-Methyl-2H-isothiazol-3-one

CAS 2682-20-4
20

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Methylisothiazolinone (MIT) — an aggressive preservative banned from leave-on cosmetics in the EU and capped at 0.0015% in rinse-off. Major cause of contact dermatitis.

Skin benefits

  • Effective broad-spectrum preservative at very low %

Known concerns

  • EU Annex V banned in leave-on
  • Severe contact allergen
  • Causing allergic contact dermatitis epidemic
  • Restricted to 0.0015% in rinse-off

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.