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Prohibited Substance

Trioxsalen [USAN]

CAS 3902-71-4
4

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

4,5',8-Trimethylpsoralen, used in PUVA photochemotherapy. EU-banned in cosmetics under Annex II — psoralens combined with UVA are IARC Group 1 carcinogens.

Skin benefits

  • Not a cosmetic ingredient

Known concerns

  • EU Annex II prohibited
  • Psoralen + UVA carcinogenic class
  • Severe photosensitizer
  • Prescription drug

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.