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Prohibited Substance

Neostigmine bromide [INN:BAN:JAN]

CAS 114-80-7
4

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An acetylcholinesterase-inhibitor drug used for myasthenia gravis. Banned in EU cosmetics under Annex II — cholinergic drugs cause systemic toxicity and have no cosmetic application.

Skin benefits

  • Not a cosmetic ingredient

Known concerns

  • EU Annex II prohibited
  • Acetylcholinesterase inhibitor
  • Pharmaceutical-only
  • Acute systemic toxicity if absorbed

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.