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Synthetic peptide

SH-POLYPEPTIDE-165

72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A biotechnology-derived synthetic polypeptide designed to mimic human signaling factors. Used in anti-aging formulas for fibroblast support, with limited but generally favorable tolerability data.

Function

SOLVENT

Skin benefits

  • Biotech-derived synthetic polypeptide mimicking growth factor signaling
  • May support fibroblast activity and collagen turnover
  • Used in anti-aging serums for cellular renewal claims
  • Generally well tolerated at low cosmetic use levels

Known concerns

  • Limited public safety dossier and no SCCS opinion to date
  • Mechanism of action and skin penetration not fully validated
  • Possible sensitization in atopic skin from peptide impurities

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.