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Synthetic peptide

PENTAPEPTIDE-65

72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A pentapeptide used in skincare as a signaling peptide aimed at supporting collagen and skin renewal. The pentapeptide class is generally well-tolerated, but specific data for the -65 variant is limited.

Function

SKIN CONDITIONING

Skin benefits

  • Pentapeptides are typically used to signal skin-repair pathways
  • May support collagen synthesis and improve fine-line appearance
  • Generally well-tolerated at the low concentrations used in serums

Known concerns

  • Pentapeptide-65 specifically lacks published peer-reviewed studies
  • Marketing claims often outpace clinical evidence
  • Stability and skin penetration vary by formulation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Check your shelf

Find PENTAPEPTIDE-65 in your products.

Scan any cosmetic product with LuxSense to see if it contains PENTAPEPTIDE-65 and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.