S-CANNABIS SATIVA PENTAPEPTIDE-1
Conditioning Agent
Good
About S-CANNABIS SATIVA PENTAPEPTIDE-1
A synthetically produced pentapeptide inspired by the edestin 1 protein sequence from Cannabis sativa, designed to mimic the skin-barrier and anti-inflammatory properties of the parent plant protein without containing any psychoactive cannabinoids.
Detailed Analysis
s-Cannabis Sativa Pentapeptide-1 is a synthetic single-chain pentapeptide (Ala-Cys-Leu-Pro-Ser-Trp-Val in a repeating/cyclic pattern) derived from a segment of edestin 1, a storage protein from Cannabis sativa seeds. It contains no psychoactive cannabinoids (THC, CBD) and is produced via solid-phase peptide synthesis, ensuring batch-to-batch consistency and absence of plant contaminants. Peptides of this size generally have poor dermal penetration and act primarily at the skin surface. No specific EU restrictions apply to this peptide, which falls outside the scope of Annex III/1 substances.
What It Does
Skin Benefits
- ✓ May support skin barrier function through peptide signaling
- ✓ Anti-inflammatory potential via suppression of pro-inflammatory cytokines
- ✓ Plant-derived inspiration suggests skin conditioning benefits
Known Concerns
- ⚠ Limited published clinical safety data specifically for this peptide sequence
- ⚠ Peptide purity critical — synthesis impurities may cause irritation
- ⚠ Not all peptide sequences in cosmetics have been systematically reviewed by SCCS
Safety Score
Good
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
Check your products for S-CANNABIS SATIVA PENTAPEPTIDE-1
Scan any cosmetic product to see if it contains this ingredient and get a full safety breakdown.
Download LuxSenseThis information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.