Skip to content

Banned Substance

procaine

CAS 59-46-1
6

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A classic ester-type local anaesthetic (Novocaine). Procaine and its salts are listed in EU Annex II as prohibited cosmetic ingredients — pharmacologically active and a known contact allergen.

Skin benefits

  • Not applicable — not permitted in cosmetics

Known concerns

  • EU Annex II prohibited
  • Ester anaesthetic allergen
  • Cross-reacts with other PABA-derived anaesthetics
  • Systemic activity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related banned substances

6
1,2-Epoxy-3-phenoxypropane (Phenylglycidyl ether)
Banned Substance
 6
Fluazifop-P-butyl (ISO)
Banned Substance
 6
METHOXYETHANOL
Banned Substance
 6
codoxime
Banned Substance
 5
(E)-3-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
Banned Substance
 5
1-Ethyl-1-methylmorpholinium bromide
Banned Substance
 5
16-BETA METHYL ESTRADIOLPROPANOATE
Banned Substance
 5
2-(4-tert-Butylphenyl)ethanol
Banned Substance

Check your shelf

Find procaine in your products.

Scan any cosmetic product with LuxSense to see if it contains procaine and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.