Banned Substance
16-BETA METHYL ESTRADIOLPROPANOATE
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A modified estradiol (estrogen) ester. Estrogenic steroids are prohibited in cosmetics in the EU under Annex II — this ingredient should not be in skincare and is flagged red.
Function
Skin benefits
- No legitimate cosmetic-safety benefit
Known concerns
- Estrogenic steroid analogue — hormonal endocrine activity
- EU Cosmetics Regulation Annex II prohibits estrogens in cosmetics
- Endocrine disruption concern even at trace levels
- Should not appear in cosmetic products in the EU
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related banned substances
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.