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Conditioning Agent

POLYURETHANE-52

77

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A polyurethane of isophorone diisocyanate, poly(1,4-butanediol), and PEG-6 with acrylate end-caps, used in nail conditioning. Considered safe as cured polymer; aliphatic IPDI is one of the safer diisocyanate choices.

Function

NAIL CONDITIONING

Skin benefits

  • Nail conditioning and strengthening
  • Combines hardness with flexibility
  • Water-dispersible for ease of use
  • High-MW polymer with limited skin penetration

Known concerns

  • Residual isophorone diisocyanate possible
  • Residual acrylate cap monomers possible
  • Microplastic environmental persistence
  • PEG-6 component may contain trace 1,4-dioxane

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.