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Prohibited pharmaceutical

Phenylpropanolamine hydrochloride [USAN:INN:BAN]

CAS 154-41-6
3

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Phenylpropanolamine hydrochloride is a withdrawn sympathomimetic drug linked to hemorrhagic stroke risk in users. It is a controlled pharmaceutical with no place in cosmetic formulations or skincare products.

Skin benefits

  • Has historical pharmaceutical decongestant applications
  • Used in some prescription contexts in limited regions

Known concerns

  • Prescription sympathomimetic drug withdrawn in many countries
  • Associated with hemorrhagic stroke risk in humans
  • Strictly prohibited from cosmetic use
  • Has no plausible legitimate cosmetic function

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related prohibited pharmaceuticals

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.