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Prohibited pharmaceutical

Metheptazine (INN) and its salts

CAS 469-78-3
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A pharmaceutical analgesic listed under EU Cosmetics Regulation Annex II as prohibited in cosmetics. Has no place in personal care products under European law.

Skin benefits

  • Historical pharmaceutical analgesic only
  • No cosmetic function recognized

Known concerns

  • EU prohibits in cosmetics (Annex II)
  • Pharmaceutical opioid-related analgesic
  • Risk of systemic effects from topical absorption
  • No cosmetic safety profile

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related prohibited pharmaceuticals

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.