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Solvent

PERFLUOROHEXANE

CAS 355-42-0
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A perfluorinated solvent — a PFAS forever chemical that persists in water and wildlife. Topical irritation is mild but EU regulators are phasing out PFAS in cosmetics for environmental reasons.

Function

SOLVENT

Skin benefits

  • Inert solvent
  • Used in some specialty cosmetics for oxygen-carrier claims

Known concerns

  • PFAS class — extreme environmental persistence (forever chemical)
  • Skin/eye irritation (GHS H315/H319)
  • Respiratory irritant (H335)
  • Aquatic toxicity (H412)
  • EU PFAS phase-out under REACH advancing

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related solvents

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.