Solvent
PERFLUORODECALIN
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Perfluorodecalin — a perfluorocarbon used to oxygen-load skincare. Classed as a PFAS forever chemical with serious environmental persistence concerns and growing regulatory restrictions. Recommend avoiding in routine cosmetics.
Skin benefits
- Carries dissolved oxygen for skin oxygenation claims
- Smooth, light skin feel as a fluorocarbon emollient
- Used in medical perfluorocarbon emulsions historically
Known concerns
- Classified as PFAS — extreme environmental persistence (forever chemical)
- Emerging EU and national regulatory moves to restrict PFAS in cosmetics
- Bioaccumulation and ecotoxicology concerns
- Topical oxygen-carrier function may promote reactive oxygen species on skin
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related solvents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.