Preservative
OCTYLISOTHIAZOLINONE
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A potent isothiazolinone biocide — works very well but is a strong skin sensitizer. EU bans it in leave-on cosmetics and restricts rinse-off concentrations; widely flagged in contact dermatitis registries.
Skin benefits
- Effective anti-mould and anti-bacterial activity
- Active at very low concentrations
Known concerns
- Strong skin sensitizer with high allergy rates
- EU bans use in leave-on products (Annex V)
- Highly aquatic toxic
- Linked to widespread contact dermatitis
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related preservatives
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.