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Preservative

Glyoxal

CAS 107-22-2
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Glyoxal — a reactive dialdehyde flagged with mutagenicity (H341), respiratory sensitisation (H334) and irritation hazards. EU-restricted to trace residual levels only; never appropriate as an active cosmetic ingredient.

Skin benefits

  • Industrial preservative and tissue cross-linker (rarely appropriate in cosmetics)

Known concerns

  • GHS H315/H319/H335 skin/eye/respiratory irritant
  • H341 suspected germ-cell mutagen
  • H334 may cause allergy or asthma if inhaled
  • Reactive aldehyde — formaldehyde-related concerns
  • EU restricted to trace levels in cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related preservatives

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.