Antimicrobial
NONOXYNOL-12 IODINE
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
An iodine-complex of nonoxynol-12 (a nonionic surfactant) — used as a disinfectant preservative. Iodine release, irritation, and the nonoxynol/dioxane combo make it unsuitable for most modern leave-on cosmetics.
Skin benefits
- Broad-spectrum antimicrobial preservative
- Iodine-complex disinfectant action
Known concerns
- Iodine release — sensitisation and thyroid concerns
- Nonoxynol surfactant carries 1,4-dioxane residue risk
- Nonoxynol class is restricted in EU detergents
- Skin and mucous-membrane irritation
- Not recommended for leave-on cosmetics
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related antimicrobials
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.