N,N-DIMETHYL-P-PHENYLENEDIAMINE
Other
Avoid
CAS Number: 99-98-9
About N,N-DIMETHYL-P-PHENYLENEDIAMINE
A coal-tar derived p-phenylenediamine primary intermediate used in oxidative hair dyes, classified as a severe skin sensitizer under EU Annex II restriction II/1312.
Detailed Analysis
N,N-Dimethyl-p-phenylenediamine is a primary aromatic amine derivative of p-phenylenediamine (PPD), used in oxidative hair dye systems where it reacts with hydrogen peroxide to form colored dyes. The EU CosIng restriction II/1312 lists it in Annex II, prohibiting its use in cosmetic products — confirmed by the GHS hazard statements (H300, H301, H310, H311, H331) indicating acute toxicity by all routes. Hair dye ingredients structurally related to PPD are among the most restricted cosmetic substances in the EU due to severe sensitization and allergies.
Known Concerns
- ⚠ EU Annex II/1312 — PROHIBITED in cosmetic products
- ⚠ H300/H301: Fatal or toxic if swallowed
- ⚠ H310/H311: Fatal or toxic in contact with skin
- ⚠ H331: Toxic if inhaled
- ⚠ Severe skin and respiratory sensitizer — banned from cosmetic use
Safety Score
Avoid
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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Download LuxSenseThis information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.