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Preservative

CHLOROBUTANOL

CAS 57-15-8
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Chlorobutanol — a halogenated alcohol preservative tightly regulated under EU Annex V. Effective antimicrobial but with sensitization potential and chloroform-release concerns; subject to use-level and application limits.

Skin benefits

  • Antimicrobial preservation
  • Mild local anaesthetic
  • Effective at low concentrations

Known concerns

  • EU Annex V regulated preservative
  • Use-level limit (~0.5%) and not in aerosols
  • Skin sensitization potential
  • Chloroform-release on degradation
  • Mucous-membrane irritation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.