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5-tert.-Butyl-1,2,3-trimethyl-4,6-dinitrobenzene (Musk Tibetene)

CAS 145-39-1
32

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A synthetic nitromusk fragrance banned in the EU for cosmetic use due to photosensitisation risk and lack of adequate safety data.

Musk Tibetene (5-tert-butyl-1,2,3-trimethyl-4,6-dinitrobenzene) is a nitromusk compound restricted under EU Annex II/III for cosmetic use due to photosensitisation concerns and insufficient subchronic toxicity data. Its nitro-aromatic structure is associated with photoallergic contact dermatitis. The compound has been largely phased out by the fragrance industry in favour of safer alternatives.

Known concerns

  • EU restricted/banned in cosmetics due to photosensitisation
  • Insufficient subchronic and chronic toxicity data
  • Photoallergic contact dermatitis risk
  • Phased out by fragrance industry

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.