Skip to content

Other

2-NITRO-P-PHENYLENEDIAMINE

CAS 5307-14-2
32

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A nitro-substituted hair dye intermediate restricted under EU Annex II due to carcinogenic potential of its aromatic amine.

Listed under EU Annex II/1319 restriction, 2-Nitro-p-phenylenediamine is prohibited in cosmetic products due to carcinogenic concern from the p-phenylenediamine backbone. The nitro group reduction in vivo can yield mutagenic intermediates, making it unsuitable for any cosmetic application in the EU market.

Known concerns

  • EU Annex II/1319 banned substance
  • Carcinogenic concern from p-phenylenediamine moiety
  • Potential in vivo reduction to mutagenic intermediates
  • Prohibited regardless of concentration

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related others

32
1-Bromo-3,4,5-trifluorobenzene
Other
 32
2,6-Dihydroxy-4-methyl-benzaldehyde (atranol)
Other
 32
2-[2-(dimethylammonio)propyl]-1-oxo-2,2-diphenylethyl]ammonium sulphate
Other
 32
3-ETHYLAMINO-P-CRESOL SULFATE
Other
 32
5-tert.-Butyl-1,2,3-trimethyl-4,6-dinitrobenzene (Musk Tibetene)
Other
 32
BASIC VIOLET 1
Other
 32
DIISONONYL PHTHALATE
Other
 32
DISPERSE BROWN 1
Other

Check your shelf

Find 2-NITRO-P-PHENYLENEDIAMINE in your products.

Scan any cosmetic product with LuxSense to see if it contains 2-NITRO-P-PHENYLENEDIAMINE and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.