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Hair dye precursor

4-METHOXYTOLUENE-2,5-DIAMINE HCL

CAS 56496-88-9
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A methoxy-substituted aromatic diamine used as an oxidative hair dye coupler. Delivers permanent cool brown shades but carries notable sensitization risk; mandatory patch testing applies.

Skin benefits

  • Provides permanent hair color when oxidized with developer
  • Yields cool brown and ash shades in dye formulations
  • Stable on hair shaft after oxidative coupling

Known concerns

  • Aromatic diamine class with strong skin sensitization potential similar to toluene-2,5-diamine
  • Patch test required before each use due to allergic dermatitis risk
  • Restricted use as oxidative hair dye precursor only, not for direct skin or eyebrow/eyelash use
  • Salt form (HCl) of a substance subject to EU Annex III restrictions

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.