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Hair Colorant

4-HYDROXYPROPYLAMINO-3-NITROPHENOL

CAS 92952-81-3
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A nitrophenol hair-dye precursor producing red shades. EU restricts concentration and bans use on eyebrows/lashes — it is a sensitiser with low-level mutagenicity questions. Treat as a gloves-only ingredient.

Skin benefits

  • Direct/oxidative hair dye — produces red shades
  • Effective at low concentration
  • Allows shade control in colourants

Known concerns

  • EU Annex III restricted with concentration limits (max ~3% oxidative, 2.6% non-oxidative)
  • Recognised skin sensitiser
  • Nitrophenol moiety raises low-level mutagenicity questions
  • Should never be used on eyebrows or eyelashes

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.