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Hair Colorant

2-AMINO-3-HYDROXYPYRIDINE

CAS 16867-03-1
40

Safety score Β· 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A hair dye coupler used in permanent oxidative colour. EU caps it at 1% on hair and requires gloves β€” it has documented sensitisation, chromosome-damage signals in vitro, and acute oral toxicity. Treat with caution.

Skin benefits

  • Hair dye coupler β€” produces shades in oxidative colour systems
  • Effective at low concentration
  • Allows controlled colour development

Known concerns

  • Clastogenic in some in-vitro tests β€” chromosome damage
  • Documented contact sensitiser β€” patch testing recommended
  • Acute oral toxicity flagged by SCCS
  • EU Annex III restricted: max 1% on hair, professional handling advised

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.