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2-(2-OXOBUTOXY)-P-PHENYLENEDIAMINE

CAS 2839861-20-8
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

2-(2-Oxobutoxy)-P-Phenylenediamine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

This substituted p-phenylenediamine serves as a coupling intermediate in oxidative hair coloring reactions. The oxobutoxy side chain affects its reactivity profile and diffusion properties in the hair fiber. EU regulatory framework (Regulation 1223/2009 Annex III) restricts phenylenediamine-type hair dye intermediates due to their capacity to induce sensitization and potentially generate toxic oxidation by-products. Maximum permitted concentrations in ready-for-use preparations are typically limited to 2% to minimize consumer exposure and allergic response risk.

Known concerns

  • Potential skin sensitization
  • Risk of allergic reaction in sensitized individuals
  • Possible formation of reactive intermediates during oxidation
  • Cross-reactivity with para-phenylenediamine

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.