2,2'-[[4-[(2-Hydroxyethyl)amino]-3-nitrophenyl]imino]bisethanol (see note 17)
Other
Caution
CAS Number: 33229-34-4
About 2,2'-[[4-[(2-Hydroxyethyl)amino]-3-nitrophenyl]imino]bisethanol (see note 17)
A nitro-substituted aromatic amine hair dye intermediate with skin and respiratory sensitisation warnings and aquatic toxicity concerns.
Detailed Analysis
This nitro-substituted aromatic diamine hair dye precursor is regulated under EU Annex III of Cosmetics Regulation 1223/2009, with a maximum permitted concentration of 2.8% in the finished cosmetic product. The compound carries multiple hazard statements: H315 (skin irritation), H317 (skin sensitisation), H319 (eye irritation), H335 (respiratory irritation), and H412 (aquatic toxicity). The nitro group contributes to both its colour and its reactive sensitising potential. Allergic contact dermatitis from oxidative hair dyes is a well-documented concern with this class of compounds.
Known Concerns
- ⚠ Skin sensitisation (H317)
- ⚠ Skin irritation (H315)
- ⚠ Eye irritation (H319)
- ⚠ Respiratory irritation (H335)
- ⚠ Aquatic toxicity (H412)
- ⚠ EU Annex III restricted — max concentration 2.8%
Safety Score
Caution
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
Check your products for 2,2'-[[4-[(2-Hydroxyethyl)amino]-3-nitrophenyl]imino]bisethanol (see note 17)
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Download LuxSenseThis information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.