Skip to content

Other

2,2'-[[4-[(2-Hydroxyethyl)amino]-3-nitrophenyl]imino]bisethanol (see note 17)

CAS 33229-34-4
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A nitro-substituted aromatic amine hair dye intermediate with skin and respiratory sensitisation warnings and aquatic toxicity concerns.

This nitro-substituted aromatic diamine hair dye precursor is regulated under EU Annex III of Cosmetics Regulation 1223/2009, with a maximum permitted concentration of 2.8% in the finished cosmetic product. The compound carries multiple hazard statements: H315 (skin irritation), H317 (skin sensitisation), H319 (eye irritation), H335 (respiratory irritation), and H412 (aquatic toxicity). The nitro group contributes to both its colour and its reactive sensitising potential. Allergic contact dermatitis from oxidative hair dyes is a well-documented concern with this class of compounds.

Known concerns

  • Skin sensitisation (H317)
  • Skin irritation (H315)
  • Eye irritation (H319)
  • Respiratory irritation (H335)
  • Aquatic toxicity (H412)
  • EU Annex III restricted — max concentration 2.8%

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related others

48
1,2,4-Triazole
Other
 48
1-(beta-Aminoethyl)amino-4-(beta-hydroxyethyl)oxy-2-nitrobenzene and its salts
Other
 48
1-Hydroxy-4-(p-toluidino)anthraquinone
Other
 48
2,3-Dichloropropene
Other
 48
2,6-Di-Tert-Butyl-4-Methylphenol
Other
 48
2-(HYDROXYMETHOXYMETHOXY)-P-PHENYLENEDIAMINE
Other
 48
2-ETHOXYMETHOXY-P-PHENYLENEDIAMINE
Other
 48
2-METHOXYMETHYL-P-AMINOPHENOL HCL
Other

Check your shelf

Find 2,2'-[[4-[(2-Hydroxyethyl)amino]-3-nitrophenyl]imino]bisethanol (see note 17) in your products.

Scan any cosmetic product with LuxSense to see if it contains 2,2'-[[4-[(2-Hydroxyethyl)amino]-3-nitrophenyl]imino]bisethanol (see note 17) and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.