Xylometazoline

Other

32

Caution

CAS Number: 526-36-3

About Xylometazoline

Xylometazoline is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Detailed Analysis

Xylometazoline is an imidazoline derivative that causes vasoconstriction of nasal mucosa by stimulating alpha-2 adrenergic receptors. It is regulated as a medicinal product in the EU (not a cosmetic). Repeated or prolonged use can cause rhinitis medicamentosa (rebound congestion). Not listed in EU cosmetics annexes as an approved ingredient.

Known Concerns

  • Not listed in EU Cosmetics Regulation Annexes (not approved as cosmetic ingredient)
  • Risk of rebound congestion with repeated use
  • Potential cardiovascular effects from systemic absorption
  • May be restricted as a medicinal substance

Safety Score

32

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.