S-CUTIBACTERIUM ACNES OLIGOPEPTIDE-1
Conditioning Agent
Good
About S-CUTIBACTERIUM ACNES OLIGOPEPTIDE-1
A lab-made peptide used in small amounts to support skin-conditioning or repair-focused formulas. The main issue is not obvious toxicity, but limited long-term data for many newer cosmetic peptides.
Detailed Analysis
s-Cutibacterium Acnes Oligopeptide-1 is a single chain protein synthetically produced to be identical to a portion of the protein, Foldase YidC, which is found in the bacteria, Cutibacterium acnes. The peptide contains 14 amino acids. The parent protein, Foldase YidC, contains a maximum of 359 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids. Cosmetic peptides are typically used at very low concentrations for conditioning, protective, or signaling claims and are expected to have low systemic absorption from intact skin. The main uncertainty is the relatively thin independent safety literature for many newer designer peptides.
What It Does
Known Concerns
- ⚠ Limited long-term independent safety data for newer cosmetic peptides
- ⚠ May irritate very sensitive or compromised skin
Safety Score
Good
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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