S-COW OLIGOPEPTIDE-3 SP

About S-COW OLIGOPEPTIDE-3 SP

A 13-amino-acid synthetic peptide based on bovine lactoferrin, used for hair conditioning and skin conditioning in cosmetic formulations.

Detailed Analysis

S-Cow Oligopeptide-3 SP is a single-chain peptide containing 13 amino acids synthesised to match a sequence found in bovine lactoferrin, a glycoprotein in cow's milk with well-characterised antimicrobial and iron-binding properties. While the parent protein lactoferrin is well-studied and generally recognised as safe, this cosmetic oligopeptide fragment has a shorter safety history in topical products. EU Regulation (EC) No 1223/2009 does not specifically restrict lactoferrin-derived peptides; however, the SCCS has noted concerns regarding the allergenicity of cow's milk-derived ingredients in topical applications, particularly for individuals with milk protein allergies.

What It Does

Skin Benefits

• ✓ Hair conditioning benefits from lactoferrin-inspired sequence
• ✓ Skin conditioning and smoothing properties
• ✓ Lactoferrin-derived peptides may provide mild antimicrobial benefits

Known Concerns

• ⚠ Bovine-derived sequence raises potential allergenicity concern for individuals with milk protein sensitivity
• ⚠ Limited long-term safety data for this specific peptide fragment in topical cosmetics
• ⚠ The 'S-' prefix indicates potential presence of unwanted higher molecular weight proteins from incomplete purification

References