R-(SH-POLYPEPTIDE-47 SH-POLYPEPTIDE-146)
Conditioning Agent
Good
About R-(SH-POLYPEPTIDE-47 SH-POLYPEPTIDE-146)
A fused recombinant peptide combining two human peptide sequences, used in hair-care formulations for conditioning benefits.
Detailed Analysis
This fused recombinant peptide combines sh-Polypeptide-47 and sh-Polypeptide-146 sequences via gene synthesis, produced in E. coli. The resulting 246-amino-acid chain mimics natural human peptide structures. EU cosmetics regulation does not specifically restrict such recombinant fusion peptides, but they require documentation under the Cosmetics Regulation's ingredient inventory. Safety depends on production purity, particularly regarding residual host cell proteins.
What It Does
Skin Benefits
- ✓ Hair conditioning
- ✓ Film-forming protective effect
Known Concerns
- ⚠ Residual host cell protein sensitivity in sensitized individuals
Safety Score
Good
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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