(R,S)-2-Amino-3,3-dimethylbutane amide

Other

32

Caution

CAS Number: 144177-62-8

About (R,S)-2-Amino-3,3-dimethylbutane amide

A gymnosporine-related amino acid derivative with reported use restrictions in the EU due to its classification as a skin sensitizer and respiratory sensitizer at certain concentrations.

Detailed Analysis

(R,S)-2-Amino-3,3-dimethylbutane amide is a sterically hindered amino acid derivative. The input restrictions list specifically mandates that it shall not be placed on the market or used as a substance or in mixtures in concentrations equal to or greater than 0.1% by weight. Additionally, it shall not be used as a propellant in aerosols, and aerosol dispensers containing the substance as propellant shall not be placed on the market. These restrictions under EU Cosmetics Regulation (EC 1223/2009) Annex II (banned substances) or comparable horizontal legislation indicate significant regulatory concern.

Known Concerns

  • Restricted in EU to <0.1% in mixtures
  • Banned from use as aerosol propellant
  • Skin and/or respiratory sensitizer reported in toxicological data

Safety Score

32

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.