(R)-5-Bromo-3-(1-methyl-2-pyrrolidinylmethyl)-1H-indole

Other

10

Avoid

CAS Number: 143322-57-0

About (R)-5-Bromo-3-(1-methyl-2-pyrrolidinylmethyl)-1H-indole

A cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Detailed Analysis

This compound is a brominated indole alkaloid analogue with extensive hazard profiling: H302 (harmful if swallowed), H317 (may cause allergic skin reaction), H332 (harmful if inhaled), H361f (suspected fertility damage), H372 (organ damage with repeated exposure), H400/H410 (aquatic toxicity), H318 (causes serious eye damage), H361 (suspected developmental toxicity), H370 (organ damage). The combination of CMR classification, aquatic toxicity, and sensitisation alerts places this substance firmly in the restricted/banned category for cosmetic ingredients.

Known Concerns

  • Fertility and developmental toxicity (H361f, H361)
  • Organ damage with repeated exposure (H372)
  • Skin sensitisation (H317)
  • Aquatic toxicity H400, H410
  • CMR profile precluding cosmetic use

Safety Score

10

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.