QUATERNIUM-81

Conditioning Agent

72

Good

CAS Number: 97953-16-7

About QUATERNIUM-81

A quaternary ammonium conditioning agent derived from sunflower fatty acids and diethylenetriamine, used primarily for hair antistatic benefits.

Detailed Analysis

Quaternium-81 is the quaternary ammonium salt formed by the reaction of diethylenetriamine with sunflower (Helianthus annuus) seed oil fatty acids, then quaternised with dimethyl sulfate. It functions as an antistatic and hair conditioning agent. Quaternary ammonium compounds (quats) are subject to scrutiny under EU Regulation 1223/2009 Annex III; several quaternary ammonium compounds are restricted due to inhalation toxicity and sensitisation concerns (e.g., cetrimonium bromide). Quaternium-81 itself is not individually listed in Annex III but falls within a broader regulatory review of cationic surfactants; residual dimethyl sulfate (alkylating agent) is a potential concern in poorly purified grades.

What It Does

ANTISTATIC HAIR CONDITIONING

Skin Benefits

  • Antistatic agent for smooth hair feel
  • Effective hair conditioning active

Known Concerns

  • Potential residual dimethyl sulfate from quaternisation process
  • Quaternary ammonium compounds under EU Annex III regulatory review
  • Inhalation concern in aerosol/mist formulations

Safety Score

72

Good

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.