QUATERNIUM-16

Other

72

Good

CAS Number: 64425-88-3 / 35239-12-4

About QUATERNIUM-16

QUATERNIUM-16 is a cosmetic ingredient used in product formulations. Its specific function may vary depending on the product type and formulation. Exercise caution due to limited available safety data.

Detailed Analysis

Quaternium-16 (tris(2-hydroxyethyl) tallow alkyl ammonium chloride, CAS 64425-88-3) is a quaternary ammonium compound derived from tallow fatty acids. It functions as an antistatic agent and hair conditioner by adsorbing to negatively charged hair surfaces, reducing static and improving combability. Like most cationic surfactants, it can be irritating to eyes and skin at higher concentrations. No specific EU Annex restrictions apply, though quaternary ammonium compounds are monitored for ecotoxicity. The CIR Expert Panel has reviewed quaternium compounds and found them safe at typical use levels.

Skin Benefits

  • Excellent hair conditioning and detangling
  • Reduces static electricity in hair
  • Provides softness and manageability to hair

Known Concerns

  • Can cause skin and eye irritation at higher concentrations
  • Derived from animal tallow — not vegan-friendly
  • Quaternary ammonium compounds have aquatic toxicity concerns
  • Potential mild sensitizer in some individuals

Safety Score

72

Good

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.