Exfoliant
PAPAIN
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
Papain — a proteolytic enzyme from papaya that nibbles away dead surface cells for smoother, brighter skin. Generally well-tolerated, but it is a true protein allergen, so sensitive users should patch test.
Skin benefits
- Gentle enzymatic exfoliation of dead surface cells
- Smooths and brightens skin texture
- Plant-derived alternative to acid exfoliants
- Useful in rinse-off cleansers and masks
Known concerns
- Documented protein allergen with type I hypersensitivity reports
- Can sting or irritate compromised or eczematous skin
- Heat- and pH-sensitive — efficacy varies by formulation
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related exfoliants
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.