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Skin Conditioning

PALMITOYL PENTAPEPTIDE-4

CAS -
78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Palmitoyl pentapeptide-4 (Matrixyl) — a signal peptide marketed for skin firmness. Well tolerated on skin; the safety record is strong even when efficacy claims are debated.

Skin benefits

  • Skin conditioning
  • Marketed for firmness
  • Compatible with sensitive skin

Known concerns

  • Efficacy claims sometimes overstate evidence
  • Stability issues in formula
  • Premium pricing

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.